Effects of changes in diagnosis and registration on time trends in recorded childhood cancer incidence in Great Britain.
BACKGROUND: Increases in recorded childhood cancer incidence are widely reported, but do not necessarily represent real increases in risk. Time trends might conceal underlying steps caused by changes in diagnosis and registration procedures. METHODS: Using records from the National Registry of Childhood Tumours 1966-2005 (N=54650), the age-sex-standardised rate for residents of Great Britain aged under 15 years was calculated by individual year of diagnosis for each cancer subtype, and the av...Expand abstract
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