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The replication fork trap and termination of chromosome replication.

Abstract:

Bacteria that have a circular chromosome with a bidirectional DNA replication origin are thought to utilize a 'replication fork trap' to control termination of replication. The fork trap is an arrangement of replication pause sites that ensures that the two replication forks fuse within the terminus region of the chromosome, approximately opposite the origin on the circular map. However, the biological significance of the replication fork trap has been mysterious, as its inactivation has no o...

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Publication status:
Published

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Authors


Duggin, IG More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Molecular microbiology
Volume:
70
Issue:
6
Pages:
1323-1333
Publication date:
2008-12-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:7c69b1f1-1fd1-4795-afeb-da7807f84b15
Source identifiers:
31011
Local pid:
pubs:31011

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