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Nitric oxide-releasing aspirin: will it say NO to atherothrombosis?

Abstract:

Aspirin is a powerful anti-platelet drug widely used in patients with coronary atherosclerosis, but its side effects and especially its toxicity for gastrointestinal tract limit its usefulness in specific groups of patients. A new category of agents, nitric oxide-releasing aspirins (such as NCX-4016), seems to provide an alternative solution. Although this drug is still at phase II clinical trials, it has provided promising results until now. When administered in vivo, it is separated into an...

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Journal:
International journal of cardiology
Volume:
118
Issue:
2
Pages:
170-172
Publication date:
2007-05-05
DOI:
EISSN:
1874-1754
ISSN:
0167-5273
URN:
uuid:7c2e1461-ae19-4692-b2ba-5a2b4a510804
Source identifiers:
223232
Local pid:
pubs:223232

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