Journal article icon

Journal article

Exclusion of linkage between hypokalemic periodic paralysis (HOKPP) and three candidate loci.

Abstract:

Hypokalemic periodic paralysis (HOKPP) is an autosomal dominant neuromuscular disorder characterized by flaccid paralysis accompanied by lowered serum potassium levels. We have tested polymorphic markers linked to the adult skeletal muscle sodium channel (SCN4A) locus at 17q23-q25, the T-cell receptor beta (TCRB) locus at 7q35, and the H-Ras cellular proton-cogene locus (HRAS) at 11p15.5 for linkage with the affected phenotype in a single multigenerational pedigree. No evidence for genetic li...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Casley, WL More by this author
Cousin, HK More by this author
Crackower, MA More by this author
Expand authors...
Journal:
Genomics
Volume:
14
Issue:
2
Pages:
493-494
Publication date:
1992-10-05
DOI:
EISSN:
1089-8646
ISSN:
0888-7543
URN:
uuid:7c15c60d-189a-41f3-bfea-23d56eb12b81
Source identifiers:
32461
Local pid:
pubs:32461

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP