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Effect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection: A Randomized Clinical Trial.

Abstract:

Importance  Acute lower respiratory tract infection is common and often treated inappropriately in primary care with antibiotics. Corticosteroids are increasingly used but without sufficient evidence.

Objective  To assess the effects of oral corticosteroids for acute lower respiratory tract infection in adults without asthma.

Design, Setting, and Participants  Multicenter, placebo-controlled, randomized trial (July 2013 to fi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1001/jama.2017.10572

Authors


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Institution:
University of Oxford
Department:
Kellogg College
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care, Primary Care Health Sciences
Role:
Author
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National Institute for Health Research More from this funder
Publisher:
American Medical Association Publisher's website
Journal:
JAMA Journal website
Volume:
318
Issue:
8
Pages:
721-730
Publication date:
2017-08-22
Acceptance date:
2017-07-21
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
Pubs id:
pubs:724116
URN:
uri:7bd30845-1d37-4cd4-87c3-6f614b75d039
UUID:
uuid:7bd30845-1d37-4cd4-87c3-6f614b75d039
Local pid:
pubs:724116
Paper number:
8

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