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Journal article

White matter tract integrity in aging and Alzheimer's disease.

Abstract:

The pattern of degenerative changes in the brain white matter (WM) in aging, mild cognitive impairment (MCI), and Alzheimer's disease (AD) has been under debate. Methods of image analysis are an important factor affecting the outcomes of various studies. Here we used diffusion tensor imaging (DTI) to obtain fractional anisotropy (FA) measures of the WM in healthy young (n = 8), healthy elderly (n = 22), MCI (n = 8), and AD patients (n = 16). We then applied "tract-based spatial statistics" (T...

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Publication status:
Published

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Publisher copy:
10.1002/hbm.20563

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Journal:
Human brain mapping
Volume:
30
Issue:
4
Pages:
1051-1059
Publication date:
2009-04-05
DOI:
EISSN:
1097-0193
ISSN:
1065-9471
URN:
uuid:7bb70d5c-1d85-430a-b3b7-f1123597e4b9
Source identifiers:
116868
Local pid:
pubs:116868

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