Journal article icon

Journal article

Asymmetrical dimethylarginine regulates endothelial function in methionine-induced but not in chronic homocystinemia in humans: effect of oxidative stress and proinflammatory cytokines.

Abstract:

BACKGROUND: Homocystinemia is a metabolic abnormality associated with endothelial dysfunction and increased cardiovascular disease risk. The underlying mechanisms of these effects, however, are obscure. OBJECTIVE: We examined the effect of asymmetrical dimethylarginine (ADMA) on endothelial dysfunction in methionine-induced and chronic homocystinemia and evaluated the regulatory role of oxidative stress and proinflammatory cytokines on the release of ADMA. DESIGN: In this double-blind, place...

Expand abstract

Actions


Authors


Antoniades, C More by this author
Tousoulis, D More by this author
Marinou, K More by this author
Vasiliadou, C More by this author
Tentolouris, C More by this author
Expand authors...
Journal:
The American journal of clinical nutrition
Volume:
84
Issue:
4
Pages:
781-788
Publication date:
2006-10-05
EISSN:
1938-3207
ISSN:
0002-9165
URN:
uuid:7ba64ef4-149e-41c8-8cfa-72c6bb040cde
Source identifiers:
223233
Local pid:
pubs:223233

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP