- Abstract:
-
CMV-specific memory CD8(+) T cells accumulate over time to reach high frequencies amongst peripheral blood lymphocytes - a phenomenon termed 'memory inflation'. Using tetramer staining on samples from a large number of subjects and multivariate regression analysis, we were able to relate this to the phenotype of CD8(+) T cells. We made the following observations: (i) CD85j (ILT-2/LIR-1) was highly expressed alongside CD57 - an established effector memory marker - on CMV-specific CD8(+) T cell...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1440-1711.2005.01321.x
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- Journal:
- Immunology and cell biology
- Volume:
- 83
- Issue:
- 2
- Pages:
- 182-188
- Publication date:
- 2005-04-05
- DOI:
- EISSN:
-
1440-1711
- ISSN:
-
0818-9641
- URN:
-
uuid:7b8a33de-f462-4b10-a36c-d2b1c0add322
- Source identifiers:
-
13483
- Local pid:
- pubs:13483
- Copyright date:
- 2005
Journal article
Does memory improve with age? CD85j (ILT-2/LIR-1) expression on CD8 T cells correlates with 'memory inflation' in human cytomegalovirus infection.
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