Supported bilayers at the vanguard of immune cell activation studies.

Journal article

Biological adhesion between cells is critical for development of multicellular organisms and for the function of the adaptive immune system of vertebrates. A gap in understanding of adhesion systems arises from the difficulty of collecting quantitative data on the molecular interactions underlying adhesion, which is typically studied by population statistics such as percent adhesion in the presence of empirically defined forces to separate less adherent cells. Supported lipid bilayers formed ...

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Authors: Dustin, M

• Journal: Journal of structural biology
• Volume: 168
• Issue: 1
• Pages: 152-160
• Publication date: 2009-10-01
• DOI: 10.1016/j.jsb.2009.05.007
• EISSN: 1095-8657
• ISSN: 1047-8477
• Language: English
• Keywords: Animals; Immunological Synapses; Lipid Bilayers; Humans; Cell Adhesion; Models, Biological; Lymphocyte Activation; Immune System