Journal article
Blood eosinophils, fractional exhaled nitric oxide, and the risk of asthma attacks in randomised controlled trials: protocol for a systemic review and control arm patient-level meta-analysis for clinical prediction modelling
- Abstract:
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Introduction The reduction of the risk of asthma attacks is a major goal of guidelines. The fact that type-2 inflammatory biomarkers identify a higher risk, anti-inflammatory responsive phenotype is potentially relevant to this goal. We aim to quantify the relation between blood eosinophils, exhaled nitric oxide (FeNO) and the risk of severe asthma attacks.
Methods and analysis A systematic review of randomised controlled trials (RCTs) will be conducted ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 1.3MB, Terms of use)
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- Publisher copy:
- 10.1136/bmjopen-2021-058215
Authors
Bibliographic Details
- Publisher:
- BMJ Publishing Group
- Journal:
- BMJ Open More from this journal
- Volume:
- 12
- Issue:
- 4
- Article number:
- e058215
- Publication date:
- 2022-04-01
- Acceptance date:
- 2022-02-25
- DOI:
- EISSN:
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2044-6055
Item Description
- Keywords:
- Pubs id:
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1241393
- Local pid:
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pubs:1241393
- Deposit date:
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2022-02-26
Terms of use
- Copyright holder:
- Couillard et al.
- Copyright date:
- 2022
- Rights statement:
- ©2022 Author(s) (or their employer(s)). Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.
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