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Motor excitability during movement preparation in Tourette syndrome

Abstract:

Tourette syndrome (TS) is a neurodevelopmental disorder characterized by the occurrence of motor and vocal tics. TS has been linked to the impaired operation of cortical-striatal-thalamic-cortical circuits that give rise to hyper-excitability of cortical motor areas, which may be exacerbated by dysfunctional intra-cortical inhibitory mechanisms. That said, many individuals gain control over their tics during adolescence and it has been suggested that this increased control arises as a result ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1111/jnp.12033

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
James Tudor Foundation More from this funder
Publisher:
John Wiley and Sons Ltd Publisher's website
Journal:
Journal of Neuropsychology Journal website
Volume:
9
Issue:
1
Pages:
33-44
Publication date:
2015-03-05
DOI:
ISSN:
1748-6645
URN:
uuid:7b402cd5-ebb5-4a24-8f34-e095a46eeb69
Source identifiers:
541328
Local pid:
pubs:541328

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