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Pharmacological mechanisms and animal models of cognition.

Abstract:

Requirements for an effective animal model of cognition are discussed with special reference to the cholinergic hypothesis of Alzheimer's disease. It is argued, with reference to research on vasopressin and ACE inhibitors, that many putative animal models of cognition lack predictive clinical validity because they either confound the effects of cognitive and arousal processes, or fail to model a specific component of cognitive functioning. A survey of recent research on the cholinergic hypoth...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Behavioural pharmacology
Volume:
3
Issue:
4
Pages:
285-297
Publication date:
1992-08-05
EISSN:
1473-5849
ISSN:
0955-8810
URN:
uuid:7b2d881e-75df-4b03-8b5b-a5c2f532b4ce
Source identifiers:
26102
Local pid:
pubs:26102

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