Implementing novel trial methods to evaluate surgery for essential tremor
Introduction. Deep brain stimulation (DBS) can provide dramatic essential tremor (ET) relief, however no Class I evidence exists.
Materials and methods. Analysis methods: I) traditional cohort analysis; II) N-of-1 single patient randomised control trial and III) signal-to-noise (S/N) analysis. 20 DBS electrodes in ET patients were switched on and off for 3-min periods. Six pairs of on and off periods in each case, with the pair order determined ...Expand abstract
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- Neurosurgical Foundation
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- © 2015 The Neurosurgical Foundation.
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