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Production and crystallization of MHC class I B allele single peptide complexes.

Abstract:
Major histocompatibility complex class I B alleles, HLA B8, B53 and B3501 have been cloned, expressed, refolded and crystallized in specific complexes with a number of different 8-mer and 9-mer peptides. For some of these crystallization was initiated by cross-seeding between different B allele complexes. All crystallize in the space group P212121, with similar unit cell dimensions of approximately 52 A X 81 A X 112 A, contain one complex per asymmetric unit and diffract to approximately 2.0 A resolution.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, CCMP
Role:
Author
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Journal:
FEBS letters
Volume:
383
Issue:
1-2
Pages:
119-123
Publication date:
1996-03-05
DOI:
EISSN:
1873-3468
ISSN:
0014-5793
URN:
uuid:7b036b1e-e5b9-4f8b-bf3c-b9037fc544e3
Source identifiers:
28228
Local pid:
pubs:28228

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