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Journal article

Serial immunoprecipitation assays for interferon--(IFN)-beta antibodies in multiple sclerosis patients.

Abstract:

We devised a sensitive, radioimmunoprecipitation assay (RIPA) for anti-interferon (IFN)-beta-binding antibody (BAB) detection. Our RIPA showed good agreement with a reference RIPA (mean difference, -3.2 +/- 10.6 AU), and detected BAB to both IFN-beta-1a and IFN-beta-1b. Neutralizing antibodies to IFN-b (NAB) were also determined with a standard method. BAB and NAB were measured in 393 serum samples from 77 multiple sclerosis (MS) patients treated with IFN-beta-1a or -1b, who were studied over...

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Publication status:
Published

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Journal:
European cytokine network
Volume:
14
Issue:
3
Pages:
154-157
Publication date:
2003-01-01
EISSN:
1952-4005
ISSN:
1148-5493
URN:
uuid:7aedb1d2-84b0-4d82-a9b3-5b8d36f9629b
Source identifiers:
346355
Local pid:
pubs:346355

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