Journal article
Serial immunoprecipitation assays for interferon--(IFN)-beta antibodies in multiple sclerosis patients.
- Abstract:
-
We devised a sensitive, radioimmunoprecipitation assay (RIPA) for anti-interferon (IFN)-beta-binding antibody (BAB) detection. Our RIPA showed good agreement with a reference RIPA (mean difference, -3.2 +/- 10.6 AU), and detected BAB to both IFN-beta-1a and IFN-beta-1b. Neutralizing antibodies to IFN-b (NAB) were also determined with a standard method. BAB and NAB were measured in 393 serum samples from 77 multiple sclerosis (MS) patients treated with IFN-beta-1a or -1b, who were studied over...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- European cytokine network
- Volume:
- 14
- Issue:
- 3
- Pages:
- 154-157
- Publication date:
- 2003-01-01
- EISSN:
-
1952-4005
- ISSN:
-
1148-5493
- Source identifiers:
-
346355
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:346355
- UUID:
-
uuid:7aedb1d2-84b0-4d82-a9b3-5b8d36f9629b
- Local pid:
- pubs:346355
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2003
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