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Highly significant linkage to the SLI1 locus in an expanded sample of individuals affected by specific language impairment

Abstract:

Specific language impairment (SLI) is defined as an unexplained failure to acquire normal language skills despite adequate intelligence and opportunity. We have reported elsewhere a full-genome scan in 98 nuclear families affected by this disorder, with the use of three quantitative traits of language ability (the expressive and receptive tests of the Clinical Evaluation of Language Fundamentals and a test of nonsense word repetition). This screen implicated two quantitative trait loci, one o...

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Publication status:
Published

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Publisher copy:
10.1086/421529

Authors


Newbury, DF More by this author
Banfield, E More by this author
Marlow, AJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Human Genetics Wt Centre
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Journal:
AMERICAN JOURNAL OF HUMAN GENETICS
Volume:
74
Issue:
6
Pages:
1225-1238
Publication date:
2004-06-05
DOI:
ISSN:
0002-9297
URN:
uuid:7ae7b24b-8382-4cb1-905e-3cae7e70f5d4
Source identifiers:
944
Local pid:
pubs:944

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