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Journal article

Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials.

Abstract:

Published evidence suggests that aspects of trial design lead to biased intervention effect estimates, but findings from different studies are inconsistent. This study combined data from 7 meta-epidemiologic studies and removed overlaps to derive a final data set of 234 unique meta-analyses containing 1973 trials. Outcome measures were classified as "mortality," "other objective," "or subjective," and Bayesian hierarchical models were used to estimate associations of trial characteristics wit...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, CSM
Role:
Author
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Journal:
Annals of internal medicine
Volume:
157
Issue:
6
Pages:
429-438
Publication date:
2012-09-05
DOI:
EISSN:
1539-3704
ISSN:
0003-4819
URN:
uuid:7a960418-dc31-4517-99c7-f3efce6af9dd
Source identifiers:
356521
Local pid:
pubs:356521

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