Journal article
A novel vaccine strategy employing serologically different chimpanzee adenoviral vectors for the prevention of HIV-1 and HCV coinfection
- Abstract:
-
Background: Nearly 3 million people worldwide are coinfected with HIV and HCV. Affordable strategies for prevention are needed. We developed a novel vaccination regimen involving replication-defective and serologically distinct chimpanzee adenovirus (ChAd3, ChAd63) vector priming followed by modified vaccinia Ankara (MVA) boosts, for simultaneous delivery of HCV non-structural (NSmut) and HIV-1 conserved (HIVconsv) region immunogens.
Methods: We con...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Immunology Journal website
- Volume:
- 9
- Article number:
- 3175
- Publication date:
- 2019-01-18
- Acceptance date:
- 2018-12-24
- DOI:
- EISSN:
-
1664-3224
- Pmid:
-
30713538
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:966815
- UUID:
-
uuid:7a80a127-c307-43c0-9314-53c6012315de
- Local pid:
- pubs:966815
- Source identifiers:
-
966815
- Deposit date:
- 2019-02-27
Terms of use
- Copyright holder:
- Hartnell, F et al
- Copyright date:
- 2019
- Notes:
- © 2019 Hartnell, F et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
- Licence:
- CC Attribution (CC BY)
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