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Journal article

Noradrenergic modulation of space exploration in visual neglect.

Abstract:

Visual neglect after stroke is often associated with a failure to explore contralesional space. Here, we show that guanfacine, a noradrenergic agonist that modulates dorsolateral prefrontal cortex, improves leftward space exploration in selected right-hemisphere patients with neglect. The positive effects of guanfacine were associated with extended ability to maintain attention on task. The results suggest that neuropharmacological targeting of intact frontal areas might be one way to enhance...

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Publication status:
Published

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Publisher copy:
10.1002/ana.20701

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Annals of neurology
Volume:
59
Issue:
1
Pages:
186-190
Publication date:
2006-01-05
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
URN:
uuid:7a6d5e21-7bf1-4add-a941-6e5a00faba91
Source identifiers:
365304
Local pid:
pubs:365304

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