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Individual differences in premotor brain systems underlie behavioral apathy

Abstract:

Lack of physical engagement, productivity, and initiative—so-called “behavioral apathy”—is a common problem with significant impact, both personal and economic. Here, we investigate whether there might be a biological basis to such lack of motivation using a new effort and reward-based decision-making paradigm, combined with functional and diffusion-weighted imaging. We hypothesized that behavioral apathy in otherwise healthy people might be associated with differences in brain systems underl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/cercor/bhv247

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More from this funder
Funding agency for:
Husain, M
Grant:
Principal Research Fellowship
Wellcome Trust More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Cerebral Cortex Journal website
Volume:
26
Issue:
2
Pages:
807-819
Publication date:
2015-11-12
DOI:
EISSN:
1460-2199
ISSN:
1047-3211
Source identifiers:
580218
Language:
English
Keywords:
Pubs id:
pubs:580218
UUID:
uuid:7a6ada6a-ab2a-4d18-8c16-071169fd68a2
Local pid:
pubs:580218
Deposit date:
2016-02-01

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