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A control point interpolation method for the non-parametric quantification of cerebral haemodynamics from dynamic susceptibility contrast MRI.

Abstract:

DSC-MRI analysis is based on tracer kinetic theory and typically involves the deconvolution of the MRI signal in tissue with an arterial input function (AIF), which is an ill-posed inverse problem. The current standard singular value decomposition (SVD) method typically underestimates perfusion and introduces non-physiological oscillations in the resulting residue function. An alternative vascular model (VM) based approach permits only a restricted family of shapes for the residue function, w...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Journal:
NeuroImage
Volume:
64
Issue:
1
Pages:
560-570
Publication date:
2013-01-01
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
Source identifiers:
350621

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