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Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries.

Abstract:

Pulmonary arteries (PAs), particularly those of the rat, demonstrate a prominent voltage-gated K+ (Kv) current (I(Kv)), which plays an important role in the regulation of the resting potential. No detailed characterization of electrophysiological and pharmacological properties of I(Kv), particularly in resistance PA myocytes (PAMs), has been performed. The aim of the present study was therefore to compare I(Kv) in rat conduit and resistance PAMs using the standard patch clamp technique. We fo...

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Publication status:
Published

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Authors


Smirnov, SV More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Aaronson, PI More by this author
Journal:
The Journal of physiology
Volume:
538
Issue:
Pt 3
Pages:
867-878
Publication date:
2002-02-05
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
URN:
uuid:7a3b4e9a-e586-4d03-9a0d-53e559443a6a
Source identifiers:
386837
Local pid:
pubs:386837

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