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High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes.

Abstract:

OBJECTIVE: Maturity-onset diabetes of the young (MODY) as a result of mutations in hepatocyte nuclear factor 1-α (HNF1A) is often misdiagnosed as type 1 diabetes or type 2 diabetes. Recent work has shown that high-sensitivity C-reactive protein (hs-CRP) levels are lower in HNF1A-MODY than type 1 diabetes, type 2 diabetes, or glucokinase (GCK)-MODY. We aim to replicate these findings in larger numbers and other MODY subtypes. RESEARCH DESIGN AND METHODS: hs-CRP levels were assessed in 750 pati...

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Publisher copy:
10.2337/dc11-0323

Authors


McDonald, TJ More by this author
Shields, BM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
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Journal:
Diabetes Care
Volume:
34
Issue:
8
Pages:
1860-1862
Publication date:
2011-08-05
DOI:
EISSN:
1935-5548
ISSN:
0149-5992
URN:
uuid:7a1a6839-e9b0-47b7-8386-72593e634c5f
Source identifiers:
163920
Local pid:
pubs:163920

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