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Utility of VS38c in the diagnostic and prognostic assessment of osteosarcoma and other bone tumours/tumour-like lesions

Abstract:

Background:

VS38c is a monoclonal antibody that recognises a rough endoplasmic reticulum (rER) intracellular antigen termed cytoskeleton-linking membrane protein 63. rER is typically found in viable tumour cells and is abundant in osteosarcoma cells. The aim of this study was to determine the diagnostic and prognostic utility of VS38c in the histological assessment of osteosarcoma and other bone tumours/tumour-like leisons.

Methods:

Immunohistochemical s...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Version of record

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Publisher copy:
10.1186/s13569-017-0083-5

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Grigoriadis, A More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
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European Union More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Clinical Sarcoma Research Journal website
Volume:
7
Issue:
1
Pages:
17
Publication date:
2017-09-18
Acceptance date:
2017-09-06
DOI:
EISSN:
2045-3329
Pubs id:
pubs:730589
URN:
uri:79f36511-d5d9-4428-83da-3de6c6ba24c3
UUID:
uuid:79f36511-d5d9-4428-83da-3de6c6ba24c3
Local pid:
pubs:730589

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