Quantifying infarct growth and secondary injury volumes: comparing multimodal image registration measures
Background and Purpose—Lesion expansion in the week after acute stroke involves both infarct growth (IG) and anatomic distortion (AD) because of edema and hemorrhage. Enabling separate quantification would allow clinical trials targeting these distinct pathological processes. We developed an objective and automated approach to quantify these processes at 24 hours and 1 week. Methods—Patients with acute ischemic stroke were scanned at presentation, 24 hours, ... Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's Version
Centre of Excellence for Personalized Healthcare More from this funder
Engineering and Physical Sciences Research Council More from this funder
Oxford University Clinical Academic Graduate School More from this funderExpand funders...
- American Heart Association Publisher's website
- Stroke Journal website
- Publication date:
- Acceptance date:
- Pubs id:
- Local pid:
- Copyright holder:
- Harston et.al
- Copyright date:
© 2018 The Authors.
Stroke is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.