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Acute effects of interferon on estrogen receptor function do not involve the extracellular signal-regulated kinases p42mapk and p44mapk.

Abstract:

Exposure to type I interferons (IFN) increased estrogen receptor (ER) ligand binding and induced protein kinase C (PKC) translocation within 30 min but had no effect on net incorporation of [32P] into ER in Madin Darby bovine kidney (MDBK) cells. Ligand binding was also increased within 30 min by phorbol ester and the protein phosphatase inhibitor okadaic acid. Mitogen-activated protein (MAP) kinase phosphorylation was initially inhibited between 2 and 30 min and subsequently activated betwee...

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Publisher copy:
10.1089/107999000312649

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Journal:
Journal of interferon and cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Volume:
20
Issue:
2
Pages:
225-233
Publication date:
2000-02-05
DOI:
EISSN:
1557-7465
ISSN:
1079-9907
URN:
uuid:79b37b27-13ee-4c66-ba06-d7ff39f28e1c
Source identifiers:
251960
Local pid:
pubs:251960

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