Journal article icon

Journal article

Defining vitamin D status using multi-metabolite mathematical modelling: A pregnancy perspective

Abstract:

Vitamin D deficiency is linked to adverse pregnancy outcomes such as pre-eclampsia (PET) but remains defined by serum measurement of 25-hydroxyvitamin D3 (25(OH)D3) alone. To identify broader changes in vitamin D metabolism during normal and PET pregnancies we developed a relatively simple but fully parametrised mathematical model of the vitamin D metabolic pathway. The data used for parametrisation were serum vitamin D metabolites analysed for a cross-sectional group of women (n = 88); inclu...

Expand abstract
Publication status:
Published
Peer review status:
Peer Reviewed
Version:
Publisher's Version

Actions


Access Document


Files:
Publisher copy:
10.1016/j.jsbmb.2019.03.024

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Mathematical Institute
Oxford college:
New, New College
Role:
Author
ORCID:
0000-0002-9164-6565
More by this author
Role:
Author
ORCID:
0000-0003-2665-0127
Expand authors...
Publisher:
Elsevier Publisher's website
Journal:
Journal of Steroid Biochemistry and Molecular Biology Journal website
Volume:
190
Pages:
152-160
Publication date:
2019-03-26
Acceptance date:
2019-03-25
DOI:
EISSN:
1879-1220
ISSN:
0960-0760
Pubs id:
pubs:992076
URN:
uri:79a6d386-8261-4413-bf63-caa4f2d98ad9
UUID:
uuid:79a6d386-8261-4413-bf63-caa4f2d98ad9
Local pid:
pubs:992076
Language:
English
Keywords:

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP