Journal article
Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis.
- Abstract:
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BACKGROUND: Adjunctive dexamethasone reduces mortality from tuberculous meningitis, but how it produces this effect is not known. Matrix metalloproteinases (MMPs) are important in the immunopathology of many inflammatory CNS diseases thus we hypothesized that that their secretion is important in TBM and might be influenced by dexamethasone. METHODOLOGY/PRINCIPAL FINDINGS: The kinetics of cerebrospinal fluid (CSF) MMP and tissue inhibitors of MMPs (TIMPs) concentrations were studied in a subse...
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- Publication status:
- Published
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(Preview, pdf, 292.9KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0007277
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Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 4
- Issue:
- 9
- Article number:
- e7277
- Publication date:
- 2009-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
- UUID:
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uuid:79a4ac79-dfa4-40a6-8bfd-19e909d670ef
- Local pid:
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pubs:92790
- Source identifiers:
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92790
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Green et al
- Copyright date:
- 2009
- Notes:
- Copyright 2009 Green et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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