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Journal article

Repeatability and response to therapy of dynamic contrast-enhanced Magnetic Resonance Imaging biomarkers in rheumatoid arthritis in a large multicentre trial setting.

Abstract:

Objectives

To determine the repeatability, and response to therapy, of Dynamic Contrast-Enhanced (DCE) MRI biomarkers of synovitis in hand and wrist of Rheumatoid Arthritis (RA) patients, and in particular the performance of the transfer constant Ktrans, in a multicentre trial setting

Methods

DCE-MRI and RA MRI scoring (RAMRIS) were performed with meticulous standardisation at baseline, 6 and 24 weeks in a sub-study of fostamatinib monotherapy in reducing synoviti...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s00330-017-4736-9

Authors


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Institution:
University of Oxford
Oxford college:
St Peter's College
Role:
Author
Publisher:
Springer
Journal:
European Radiology More from this journal
Volume:
27
Issue:
9
Pages:
3662–3668
Publication date:
2017-01-01
Acceptance date:
2016-12-18
DOI:
EISSN:
1432-1084
ISSN:
0938-7994
Keywords:
Pubs id:
pubs:668862
UUID:
uuid:796c97a0-7d79-497d-9802-12c6cfb740cd
Local pid:
pubs:668862
Source identifiers:
668862
Deposit date:
2017-01-10

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