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Untargeted analysis of the airway proteomes of children with respiratory infections using mass spectrometry based proteomics

Abstract:

The upper airway - which consists mainly of the naso- and oro-pharynx - is the first point of contact between the respiratory system and microbial organisms that are ubiquitous in the environment. It has evolved highly specialised functions to address these constant threats whilst facilitating seamless respiratory exchange with the lower respiratory tract. Dysregulation of its critical homeostatic and defence functions can lead to ingress of pathogens into the lower respiratory tract, potenti...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1038/s41598-018-32072-3

Authors


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Institution:
University of Oxford
Division:
SE-Other
Department:
External
Role:
Author
ORCID:
0000-0002-8364-6063
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Nuffield College
Role:
Author
ORCID:
0000-0002-1236-849X
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Role:
Author
ORCID:
0000-0001-5426-1984
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
8
Issue:
1
Pages:
13814
Publication date:
2018-09-14
Acceptance date:
2018-08-23
DOI:
EISSN:
2045-2322
ISSN:
2045-2322
Pmid:
30217988
Source identifiers:
920281
Language:
English
Keywords:
Pubs id:
pubs:920281
UUID:
uuid:7962d795-c928-4ed9-bdca-cba5dc66e363
Local pid:
pubs:920281
Deposit date:
2018-12-06

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