Journal article icon

Journal article

White matter damage is associated with matrix metalloproteinases in vascular dementia.

Abstract:

BACKGROUND AND PURPOSE: Vascular disease causes multi-infarct dementia (MID) or Binswanger's disease (BD), the latter of which is a progressive form of vascular dementia (VaD) associated pathologically with fibrinoid and hyaline changes in brain arterioles with injury to the white matter. Clinically, BD patients have long-standing hypertension with disturbances of gait and intellect. Because matrix metalloproteinases (MMPs) are important in cerebral infarction, we hypothesized that disturbanc...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1161/01.str.32.5.1162

Authors


Rosenberg, GA More by this author
Sullivan, N More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Journal:
Stroke; a journal of cerebral circulation
Volume:
32
Issue:
5
Pages:
1162-1168
Publication date:
2001-05-05
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
URN:
uuid:7932ab0d-4dee-469c-9aa6-70c30a01b9ec
Source identifiers:
242336
Local pid:
pubs:242336

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP