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Increased dopamine after mating impairs olfaction and prevents odor interference with pregnancy.

Abstract:

In rodents, social odor sensing influences female reproductive status by affecting neuroendocrine cascades. The odor of male mouse urine can induce ovulation or block pregnancy within 3 d post coitus. Females avoid the action of such olfactory stimuli after embryonic implantation. The mechanisms underlying these changes are unknown. Here we report that shortly after mating, a surge in dopamine in the mouse main olfactory bulb impairs the perception of social odors contained in male urine. Tre...

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Publisher copy:
10.1038/nn.2154

Authors


Serguera, C More by this author
Kelly-Barrett, J More by this author
Banchaabouchi, MA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford
Journal:
Nature neuroscience
Volume:
11
Issue:
8
Pages:
949-956
Publication date:
2008-08-05
DOI:
EISSN:
1546-1726
ISSN:
1097-6256
URN:
uuid:78a96d0d-a4e6-41c4-8c72-bfd796aee9df
Source identifiers:
329250
Local pid:
pubs:329250

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