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Short-term monocular deprivation alters GABA in the adult human visual cortex.

Abstract:

Neuroplasticity is a fundamental property of the nervous system that is maximal early in life, within the critical period [1-3]. Resting GABAergic inhibition is necessary to trigger ocular dominance plasticity and to modulate the onset and offset of the critical period [4, 5]. GABAergic inhibition also plays a crucial role in neuroplasticity of adult animals: the balance between excitation and inhibition in the primary visual cortex (V1), measured at rest, modulates the susceptibility of ocul...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cub.2015.04.021

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
Morrone, MC More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
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Funding agency for:
Bridge, H
Publisher:
Cell Press Publisher's website
Journal:
Current biology : CB Journal website
Volume:
25
Issue:
11
Pages:
1496-1501
Publication date:
2015-06-05
DOI:
EISSN:
1879-0445
ISSN:
0960-9822
URN:
uuid:789ce649-b44d-401a-b405-91b38e432b11
Source identifiers:
525433
Local pid:
pubs:525433
Language:
English

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