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Transcriptome-based identification of candidate membrane proteins.

Abstract:

A full understanding of leukocyte responses to external stimuli requires knowledge of the full complement of proteins found on their surfaces. Systematic examination of the mammalian cell surfaces at the protein level is hampered by technical difficulties associated with proteomic analysis of so many membrane proteins and the large amounts of starting material required. The use of transcriptomic analyses avoids challenges associated with protein stability and separation and enables the inclus...

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Publisher copy:
10.1007/978-1-60327-310-7_3

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Medicine Division
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
528
Pages:
37-56
Publication date:
2009
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
URN:
uuid:7899a278-c890-48e4-830a-d98240820495
Source identifiers:
21898
Local pid:
pubs:21898

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