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The presence of anticardiolipin antibodies in adults may be influenced by infections in infancy.

Abstract:

OBJECTIVES: There has been limited success defining environmental factors important in the development of antiphospholipid (Hughes) syndrome (APS). Recent work suggests that the perinatal environment may be important in the development of other autoimmune diseases. We measured anticardiolipin antibodies (aCL) in a general population with well-defined early lives to see whether fetal and infant growth and infections were associated with aCL positivity in adult life. METHODS: aCLs were measured...

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Publication status:
Published

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Publisher copy:
10.1093/qjmed/hcm119

Authors


Edwards, CJ More by this author
Syddall, H More by this author
Jameson, K More by this author
Williams, EL More by this author
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Journal:
QJM : monthly journal of the Association of Physicians
Volume:
101
Issue:
1
Pages:
41-47
Publication date:
2008-01-05
DOI:
EISSN:
1460-2393
ISSN:
1460-2725
URN:
uuid:788578ed-5fd7-40f2-9331-f0daf3d9d211
Source identifiers:
125511
Local pid:
pubs:125511

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