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The systemic and local acute phase response following acute brain injury.

Abstract:

It is not known whether acute brain injury results in a systemic acute phase response (APR) or whether an APR influences outcome after an insult to the CNS. The present study sought to establish whether brain injury elicits a systemic or local APR. The expression of acute phase protein (APP) mRNA in liver and brain tissues was measured by Taqman reverse transcriptase-polymerase chain reaction after an excitotoxic lesion in the striatum or challenge with a proinflammatory cytokine. N-methyl-d-...

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Publication status:
Published

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Authors


Wilcockson, DC More by this author
Campbell, SJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Journal:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Volume:
22
Issue:
3
Pages:
318-326
Publication date:
2002-03-05
DOI:
EISSN:
1559-7016
ISSN:
0271-678X
URN:
uuid:7883c990-e6fd-4ebd-bcea-b5764df99da3
Source identifiers:
383081
Local pid:
pubs:383081

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