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Dual role of a viral polymerase in viral genome replication and particle self-assembly

Abstract:

Double-stranded RNA (dsRNA) viruses package several RNA-dependent RNA polymerases (RdRp) together with their dsRNA genome into an icosahedral protein capsid known as the polymerase complex. This structure is highly conserved among dsRNA viruses but is not found in any other virus group. RdRp subunits typica...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1128/mBio.01242-18

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Structural Biology
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Structural Biology
ORCID:
0000-0002-0348-7323
Poranen, MM More by this author
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Funding agency for:
Ilca, SL
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Funding agency for:
Huiskonen, JT
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Funding agency for:
Poranen, MM
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Publisher:
American Society for Microbiology Publisher's website
Journal:
mBio Journal website
Volume:
9
Issue:
5
Pages:
Article: e01242-18
Publication date:
2018-10-02
Acceptance date:
2018-08-24
DOI:
ISSN:
2150-7511
Pubs id:
pubs:923908
URN:
uri:787e2400-5bb9-47e7-ac4d-d2070f8b4504
UUID:
uuid:787e2400-5bb9-47e7-ac4d-d2070f8b4504
Local pid:
pubs:923908

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