Management of intestinal failure in inflammatory bowel disease: small intestinal transplantation or home parenteral nutrition?

Journal article

Inflammatory bowel disease and Crohn's disease in particular, is a common cause of intestinal failure. Current therapeutic options include home parenteral nutrition and intestinal transplantation. For most patients, home intravenous therapy including parenteral nutrition, with a good probability of long-term survival, is the favoured choice. However, in selected patients, with specific features that may shorten survival or complicate home parenteral nutrition, intestinal transplantation presents a viable alternative. We present survival, complications, quality of life and economic considerations that currently influence individualised decision-making between home parenteral nutrition and intestinal transplantation.

Authors: Harrison, E; Allan, P; Ramu, A; Vaidya, A; Travis, S

• Publication status: Published
• Publisher: WJG Press
• Journal: World journal of gastroenterology : WJG
• Volume: 20
• Issue: 12
• Pages: 3153-3163
• Publication date: 2014-03-01
• DOI: 10.3748/wjg.v20.i12.3153
• EISSN: 2219-2840
• ISSN: 1007-9327
• Language: English
• Keywords: Crohn’s disease; Complications; Inflammatory bowel disease; Home parenteral nutrition; Intestinal transplantation; Quality of life; Intestinal failure; Survival