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Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.

Abstract:

BACKGROUND: Accumulating evidence suggests that risk factors for classical Hodgkin lymphoma (cHL) differ by tumor Epstein-Barr virus (EBV) status. This potential etiological heterogeneity is not recognized in current disease classification. METHODS: We conducted a genome-wide association study of 1200 cHL patients and 6417 control subjects, with validation in an independent replication series, to identify common genetic variants associated with total cHL and subtypes defined by tumor EBV stat...

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Publication status:
Published

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Publisher copy:
10.1093/jnci/djr516

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Journal:
Journal of the National Cancer Institute
Volume:
104
Issue:
3
Pages:
240-253
Publication date:
2012-02-05
DOI:
EISSN:
1460-2105
ISSN:
0027-8874
URN:
uuid:77f7df9b-0225-47f5-8c85-72c350de189f
Source identifiers:
245881
Local pid:
pubs:245881

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