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Human non-contrast T1 values and correlation with histology in diffuse fibrosis

Abstract:

Background: Aortic stenosis (AS) leads to diffuse fibrosis in the myocardium, which is linked to adverse outcome. Myocardial T1 values change with tissue composition. Objective: To test the hypothesis that our recently developed non-contrast cardiac magnetic resonance (CMR) T1 mapping sequence could identify myocardial fibrosis without contrast agent. Design, setting and patients: A prospective CMR non-contrast T1 mapping study of 109 patients with moderate and severe AS and 33 age- and gende...

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Journal:
Heart
Volume:
99
Issue:
13
Pages:
932-937
Publication date:
2013-07-05
DOI:
EISSN:
1468-201X
ISSN:
1355-6037
URN:
uuid:77f60196-817b-4172-b328-6f057fd316cf
Source identifiers:
406043
Local pid:
pubs:406043
Language:
English

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