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Paxillin and ponsin interact in nascent costameres of muscle cells.

Abstract:

Muscle differentiation requires the transition from motile myoblasts to sessile myotubes and the assembly of a highly regular contractile apparatus. This striking cytoskeletal remodelling is coordinated with a transformation of focal adhesion-like cell-matrix contacts into costameres. To assess mechanisms underlying this differentiation process, we searched for muscle specific-binding partners of paxillin. We identified an interaction of paxillin with the vinexin adaptor protein family member...

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Publisher copy:
10.1016/j.jmb.2007.03.050

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Role:
Author
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Journal:
Journal of molecular biology
Volume:
369
Issue:
3
Pages:
665-682
Publication date:
2007-06-05
DOI:
EISSN:
1089-8638
ISSN:
0022-2836
URN:
uuid:77f3a473-8e0a-45f9-93d0-b655612bbd25
Source identifiers:
261998
Local pid:
pubs:261998

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