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Thesis

Fluorescence studies of influenza RNA and RNA polymerase

Abstract:

The influenza A virus genome consists of eight single-stranded segments of negativesense viral RNA (vRNA) with highly conserved, partially complementary termini. These termini associate in a double-stranded RNA structure, known as a panhandle, which is bound by the viral RNA-dependent RNA polymerase and can serve as a promoter in both viral transcription and replication.

In part A of this thesis, I use a combination of classical biochemistry techniques and fluorescence techniques (b...

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Institution:
University of Oxford
Oxford college:
Balliol College
Department:
Mathematical,Physical & Life Sciences Division - Physics - Condensed Matter Physics
Role:
Author

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Role:
Supervisor
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Funding agency for:
Alexandra Iulia Tomescu
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:77f33f82-76f7-4154-912e-5c92bd4bf9c6
Local pid:
ora:12489

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