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Journal article : Review

Bile acids as drivers and biomarkers of hepatocellular carcinoma

Abstract:

The prevalence of hepatocellular carcinoma (HCC) is rapidly increasing, driven not least in part by the escalating prevalence of non-alcoholic fatty liver disease. Bile acid (BA) profiles are altered in patients with HCC and there is a developing body of evidence from in vitro human cellular models as well as rodent data suggesting that BA are able to modulate fundamental processes that impact on cellular phenotype predisposing to the development of HCC including senescence, proliferation ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4254/wjh.v14.i9.1730

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Oxford college:
Keble College
Role:
Author
ORCID:
0000-0002-3170-8533
Publisher:
Baishideng Publishing Group
Journal:
World Journal of Hepatology More from this journal
Volume:
14
Issue:
9
Pages:
1730-1738
Publication date:
2022-09-27
Acceptance date:
2022-08-16
DOI:
EISSN:
1948-5182
Pmid:
36185719
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1285463
Local pid:
pubs:1285463
Deposit date:
2023-01-16

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