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Thesis

Cell and tissue specific functional genomics of psoriasis and psoriatic arthritis

Abstract:

Psoriasis and psoriatic arthritis (PsA) are chronic inflammatory diseases mainly affecting the skin and joints that result from the interaction of genetic and environmental factors. Despite the success of genome-wide association studies (GWAS) in uncovering genetic risk loci, the functional mechanisms underlying these associations remain largely unresolved. This thesis aims to establish genome-wide epigenetic and gene expression profiles for immune cells isolated from blood and disease-rel...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Supervisor
Department:
Faculty of Medicine, School of Public Health, Imperial College London
Role:
Supervisor
Psoriasis Association UK More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:7796bc0b-0171-46b6-9d3d-143cf4914eec
Deposit date:
2020-05-02

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