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The European Consortium on MEN1. Linkage disequilibrium studies in multiple endocrine neoplasia type 1 (MEN1).

Abstract:

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by tumours of the parathyroids, pancreas and anterior pituitary. The MEN1 gene has been localised to a 2-Mb region of chromosome 11q13 by meiotic mapping studies in MEN1 families. Such studies may have a limited resolution of approximately 1 cM (i.e. 1 Mb) and we have therefore investigated 96 MEN1 families (40 British, 17 French, 12 Finnish, 7 Swedish, 7 Dutch, 7 North American, 2 Australian, 1 New Zea...

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Publisher copy:
10.1007/s004390050569

Authors


Bassett, JHD More by this author
Pannett, AAJ More by this author
Forbes, SA More by this author
Thakker, RV More by this author
McCarthy, M More by this author
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Journal:
Human genetics
Volume:
100
Issue:
5-6
Pages:
657-665
Publication date:
1997-10-05
DOI:
EISSN:
1432-1203
ISSN:
0340-6717
URN:
uuid:778f168a-7e74-49e6-85a2-fbfe639b6c30
Source identifiers:
94315
Local pid:
pubs:94315

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