Journal article
Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates.
- Abstract:
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The development of an efficacious Plasmodium falciparum malaria vaccine remains a top priority for global health. Vaccination with irradiated sporozoites is able to provide complete sterile protection through the action of CD8(+) T cells at the liver-stage of infection. However, this method is currently unsuitable for large-scale deployment and focus has instead turned to the development of sub-unit vaccines. Sub-unit vaccine efforts have traditionally focused on two well-known pre-erythrocyt...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1001.5KB, Terms of use)
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- Publisher copy:
- 10.1038/srep11820
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Funding
Bibliographic Details
- Publisher:
- Nature Publishing Group
- Journal:
- Scientific reports More from this journal
- Volume:
- 5
- Pages:
- 11820
- Publication date:
- 2015-07-01
- Acceptance date:
- 2015-06-01
- DOI:
- EISSN:
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2045-2322
- ISSN:
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2045-2322
Item Description
- Language:
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English
- Pubs id:
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pubs:531457
- UUID:
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uuid:777ef3c6-29c9-4635-835c-44fb68ae2c28
- Local pid:
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pubs:531457
- Source identifiers:
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531457
- Deposit date:
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2015-12-03
Terms of use
- Copyright holder:
- Longley et al
- Copyright date:
- 2015
- Notes:
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This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce
the material.
- Licence:
- CC Attribution (CC BY)
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