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Comparison of a therapeutic‐only versus prophylactic platelet transfusion policy for people with congenital or acquired bone marrow failure disorders

Abstract:

Background

Bone marrow disorders encompass a group of diseases characterised by reduced production of red cells, white cells, and platelets, or defects in their function, or both. The most common bone marrow disorder is myelodysplastic syndrome. Thrombocytopenia, a low platelet count, commonly occurs in people with bone marrow failure. Platetet transfusions are routinely used in people with thrombocytopenia secondary to bone marrow failure disorders to treat or prevent bleeding. ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1002/14651858.CD012342.pub2

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; NPEU
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; Weatherall Insti. of Molecular Medicine
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; Clinical Laboratory Sciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
ORCID:
0000-0002-6881-6984
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NHS Blood and Transplant More from this funder
National Institute for Health Research More from this funder
Publisher:
Wiley Publisher's website
Journal:
Cochrane Database of Systematic Reviews Journal website
Volume:
2018
Issue:
5
Pages:
CD012342
Publication date:
2018-05-14
Acceptance date:
2018-05-11
DOI:
EISSN:
1469-493X
Pubs id:
pubs:847940
URN:
uri:776cef79-535c-4f45-ae3b-9252fb15d5c4
UUID:
uuid:776cef79-535c-4f45-ae3b-9252fb15d5c4
Local pid:
pubs:847940

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