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Thesis

Clinical and biochemical features of Parkinson’s disease: A cross-sectional and longitudinal analysis of the Oxford Discovery cohort dataset

Abstract:

Parkinson’s disease (PD) is a heterogenous multisystem neurodegenerative disorder displaying a marked variation in phenotype and prognosis. Predicting prognosis has important implications for individual prognostication, empowering clinical trials and targeting novel treatments. This study examined which clinical and biochemical factors predicted prognosis in a large cohort of early PD subjects (Discovery cohort, n=945).

A systematic review revealed evidence that older age at onset,...

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Department:
University of Oxford
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Author

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Department:
University of Bristol
Role:
Supervisor
Department:
University of Oxford
Role:
Supervisor
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Grant:
INN-14A-37
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Project
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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