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Thesis

Clinical and biochemical features of Parkinson’s disease: A cross-sectional and longitudinal analysis of the Oxford Discovery cohort dataset

Abstract:

Parkinson’s disease (PD) is a heterogenous multisystem neurodegenerative disorder displaying a marked variation in phenotype and prognosis. Predicting prognosis has important implications for individual prognostication, empowering clinical trials and targeting novel treatments. This study examined which clinical and biochemical factors predicted prognosis in a large cohort of early PD subjects (Discovery cohort, n=945).

A systematic review revealed evidence that older age at onset,...

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Division:
MSD
Department:
Clinical Neurosciences
Department:
University of Oxford
Role:
Author

Contributors

Department:
University of Bristol
Role:
Supervisor
Department:
University of Oxford
Role:
Supervisor
Monument Trust Discovery Award More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:776658b3-f6eb-4988-8768-9a7581cf660f
Deposit date:
2018-09-02

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