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Deep brain stimulation for chronic pain

Abstract:
As a clinical intervention, deep brain stimulation (DBS) has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders including chronic pain. In this review, we concentrate on the experience of using DBS to treat chronic pain in Oxford. We provide a brief historical background as well as details of our methods for patient selection, surgical techniques and assessment. While the precise mechanisms of action for DBS remain uncertain, we describe how DBS can help for treatment-resistant chronic pain and have great potential to advance our general understanding of the human brain. In particular, we show how DBS can be used in conjunction with methods such as local field potentials and magnetoencephalography to map the underlying mechanisms of normal and abnormal oscillatory synchronization in the brain related to the pleasure of pain relief. © 2010 by Nova Science Publishers, Inc. All rights reserved.

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author


Publisher:
Nova Science Publishers, Inc.
Host title:
Pain. Brain Stimulation in the Treatment of Pain
Pages:
47-68
Publication date:
2011-01-01
ISBN:
9781608766901


Pubs id:
pubs:374965
UUID:
uuid:7751a036-3890-4362-8ee9-0056a3f657aa
Local pid:
pubs:374965
Source identifiers:
374965
Deposit date:
2014-02-14

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