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Adjuvanting a viral vectored vaccine against pre-erythrocytic malaria

Abstract:

The majority of routinely given vaccines require two or three immunisations for full protective efficacy. Single dose vaccination has long been considered a key solution to improving the global immunisation coverage. Recent infectious disease outbreaks have further highlighted the need for vaccines that can achieve full efficacy after a single administration. Viral vectors are a potent immunisation platform, benefiting from intrinsic immuno-stimulatory features while retaining excellent safet...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41598-017-07246-0

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
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Funding agency for:
Hill, A
Grant:
Strategic Award (100157/Z/12/Z
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Funding agency for:
Reyes-Sandoval, A
Grant:
Career Development Fellowship Award (097395
More from this funder
Grant:
Strategic Award (100157/Z/12/Z) to AH
Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Issue:
1
Article number:
7284
Publication date:
2017-08-04
DOI:
ISSN:
2045-2322
Language:
English
Pubs id:
pubs:713193
UUID:
uuid:773add9e-10aa-4d81-9f86-654e8c93569a
Local pid:
pubs:713193
Deposit date:
2017-08-11

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