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Adjuvanting a viral vectored vaccine against pre-erythrocytic malaria

Abstract:

The majority of routinely given vaccines require two or three immunisations for full protective efficacy. Single dose vaccination has long been considered a key solution to improving the global immunisation coverage. Recent infectious disease outbreaks have further highlighted the need for vaccines that can achieve full efficacy after a single administration. Viral vectors are a potent immunisation platform, benefiting from intrinsic immuno-stimulatory features while retaining excellent safet...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/s41598-017-07246-0

Authors


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Department:
Oxford, MSD, NDM, Jenner Institute
Role:
Author
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Department:
Oxford, MSD, NDM
Role:
Author
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Department:
Oxford, MSD, NDM, Jenner Institute
Role:
Author
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Funding agency for:
Hill, AVS
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Funding agency for:
Reyes-Sandoval, A
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Grant:
Career Development Fellowship Award (097395) to ARS
Strategic Award (100157/Z/12/Z) to AH
Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Issue:
1
Pages:
Article: 7284
Publication date:
2017-08-04
DOI:
ISSN:
2045-2322
Pubs id:
pubs:713193
URN:
uri:773add9e-10aa-4d81-9f86-654e8c93569a
UUID:
uuid:773add9e-10aa-4d81-9f86-654e8c93569a
Local pid:
pubs:713193
Paper number:
1
Language:
English

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